"Raman Raghav 2.0" is a crime thriller that revolves around the story of Raman Raghav (played by Arjun Manhas), a notorious serial killer who is terrorizing the city of Mumbai. The film takes place several years after the events of the first movie and follows the character of ACP Siddharth (played by Rajkummar Rao), who is tasked with capturing Raman Raghav.