"Wrong Turn 2: Dead End" takes place a year after the events of the first film. A group of young friends, all aspiring actors, are on their way to a casting call in Hollywood. However, their journey takes a deadly turn when they stumble upon a remote highway, which leads them to a secluded area inhabited by a group of cannibals. The group soon finds themselves trapped and hunted by the cannibals, led by the infamous Three Fingers.